PolySearch2 - Given Bisphenol A, Find


ZScore RScore Entity ID Name Synonyms Hits
12.67 85 DID38503 Diabetes mellitus Diabetes mellitus; DM - Diabetes mellitus; diabetes; Diabetes mellitus (disorder); Diabetes nos... (Read More) 5 [0, 0, 3, 2]
5.44 45 DID40143 Autistic thinking Autistic thinking; Autism... (Read More) 5 [0, 0, 1, 4]
3.63 35 DID06289 Ovarian Carcinoma Ovarian Carcinoma; Ovarian Cancers; CARCINOMA OF OVARY; Ovary Cancer; Cancer of the Ovary; Cancer of Ovary; Ovarian Cancer; Ovary Cancers; OVARIAN CARCINOMA; Cancer, Ovarian... (Read More) 3 [0, 0, 1, 2]
3.63 35 DID49494 Generalized metabolic disorder Generalized metabolic disorder; METABOLIC DISORDERS; Diseases, Metabolic; Metabolic disease; Thesaurismosis; Metabolic disorder; Thesaurismoses; Metabolic Diseases; metabolism disorder; Disease, Metab... (Read More) 3 [0, 0, 1, 2]
2.73 30 DID44631 infertility infertility; Infertile; Difficulty conceiving... (Read More) 2 [0, 0, 1, 1]
2.73 30 DID06582 breast neoplasm breast neoplasm; Breast tumour; Neoplasm of breast; Breast Neoplasm; Tumors, Breast; Breast Tumor; Tumor of the Breast; Tumor, Breast; mammary tumor; Breast Neoplasms; Tumor of breast; Tumour of breas... (Read More) 2 [0, 0, 1, 1]
2.73 30 DID71361 Obesity Obesity... (Read More) 2 [0, 0, 1, 1]
2.73 30 DID06945 LIVER FATTY CHANGE LIVER FATTY CHANGE; Liver Steatosis; hepatic steatosis; Steatosis of liver; Hepatic lipidosis; STEATOSIS HEPATIC; LIVER FATTY; Liver, Fatty; LIVER FATTY DEGENERATION; Fatty change of liver; Fatty live... (Read More) 2 [0, 0, 1, 1]
2.73 30 DID31595 Diabetes Mellitus, Type II Diabetes Mellitus, Type II; MODY; DIABETES, MATURITY ONSET; Diabetes Mellitus, Non Insulin Dependent; NIDDM - Non-insulin dependent diabetes mellitus; Diabetes Mellitus, Type 2; AODM; Type 2 diabetes ... (Read More) 2 [0, 0, 1, 1]
1.83 25 DID40352 tumorigenesis tumorigenesis; oncogenesis; Tumorigenesis... (Read More) 1 [0, 0, 1, 0]
1.83 25 DID61015 Poor glycaemic control Poor glycaemic control; Poor glycemic control... (Read More) 1 [0, 0, 1, 0]
1.83 25 DID70477 Disease Disease... (Read More) 5 [0, 0, 0, 5]
1.83 25 DID34674 Cardiovascular Diseases Cardiovascular Diseases; CVS disease; Cardiovascular Disorder; Disease, Cardiovascular; Diseases, Cardiovascular; Cardiovascular system disease; Cardiovascular Disorders; DISORDER CARDIOVASCULAR; Dise... (Read More) 1 [0, 0, 1, 0]
1.83 25 DID32555 Atopic neurodermatitis Atopic neurodermatitis; Atopic Dermatitis; Disseminated neurodermatitis; Besnier's prurigo; ECZEMA, ATOPIC; Atopic Eczema; AD - Atopic dermatitis; DERMATITIS ALLERGIC; Allergic eczema; Allergic dermat... (Read More) 1 [0, 0, 1, 0]

Associated Diseases - DID38503 : Diabetes mellitus

ZScoreRScoreEntity TypeIDNameSynonyms
12.6695078097 85 - [0, 0, 3, 2] Diseases DID38503 Diabetes mellitus Diabetes mellitus; DM - Diabetes mellitus; diabetes; Diabetes mellitus (disorder); Diabetes nos

Evidence Section : DID38503 - MEDLINE

RScore Document Snippets
55 - [0, 0, 2, 1] Bisphenol A: What lies beneath its induced diabetes and the epigenetic modulation?
[MEDLINE : 30359670]
(2018) Bisphenol A: What lies beneath its induced diabetes and the epigenetic modulation?. Life sciences;Life Sci;2018 Dec;214:136-144

- Nowadays, endocrine disrupting chemical pollution has become one of the major concerns due to the potential role of these chemicals in provoking endocrine disorders especially type 2 diabetes.

- Bisphenol A: What lies beneath its induced diabetes and the epigenetic modulation?

- As a widespread endocrine disrupting chemical, Bisphenol A, with modest estrogenic activity can exert its detrimental effects in the different organs involved in type 2 diabetes such as pancreas, liver, adipocyte and skeletal muscles.

25 - [0, 0, 1, 0] Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes.
[MEDLINE : 31004310]
(2019) Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes. Molecular and cellular biochemistry;Mol. Cell. Biochem.;2019 Aug;458(1-2):171-183

- Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes.

5 - [0, 0, 0, 1] The adverse effect of 4-tert-octylphenol on fat metabolism in pregnant rats via regulation of lipogenic proteins.
[MEDLINE : 26164745]
(2015) The adverse effect of 4-tert-octylphenol on fat metabolism in pregnant rats via regulation of lipogenic proteins. Environmental toxicology and pharmacology;Environ. Toxicol. Pharmacol.;2015 Jul;40(1):284-91

- The alteration of nutritional intake and fat metabolism may affect the maintenance of pregnancy and supplementation of nutrients to the fetus, and therefore can cause severe metabolic diseases such as ketosis, marasmus and diabetes mellitus in pregnant individuals.


Associated Diseases - DID40143 : Autistic thinking

ZScoreRScoreEntity TypeIDNameSynonyms
5.4412624666 45 - [0, 0, 1, 4] Diseases DID40143 Autistic thinking Autistic thinking; Autism

Evidence Section : DID40143 - MEDLINE

RScore Document Snippets
45 - [0, 0, 1, 4] Autism genes are selectively targeted by environmental pollutants including pesticides, heavy metals, bisphenol A, phthalates and many others in food, cosmetics or household products.
[MEDLINE : 27984170]
(2016) Autism genes are selectively targeted by environmental pollutants including pesticides, heavy metals, bisphenol A, phthalates and many others in food, cosmetics or household products. Neurochemistry international;Neurochem. Int.;2016 Oct;:

- Autism polymorphisms influence the sensitivity to some of these chemicals and these same genes play an important role in barrier function and control of respiratory cilia sweeping particulate matter from the airways.

- Further epidemiological studies and neurodevelopmental and behavioural research is warranted to determine the relevance of large number of suspect candidates whose addition to the environment, household, food and cosmetics might be fuelling the autism epidemic in a gene-dependent manner.

- Gene/environment interactions in autism were analysed using 206 autism susceptibility genes (ASG 's) from the Autworks database to interrogate ∼1 million chemical/gene interactions in the comparative toxicogenomics database.

- Autism genes are selectively targeted by environmental pollutants including pesticides, heavy metals, bisphenol A, phthalates and many others in food, cosmetics or household products.

- The increasing incidence of autism suggests a major environmental influence.


Associated Diseases - DID06289 : Ovarian Carcinoma

ZScoreRScoreEntity TypeIDNameSynonyms
3.63420113083 35 - [0, 0, 1, 2] Diseases DID06289 Ovarian Carcinoma Ovarian Carcinoma; Ovarian Cancers; CARCINOMA OF OVARY; Ovary Cancer; Cancer of the Ovary; Cancer of Ovary; Ovarian Cancer; Ovary Cancers; OVARIAN CARCINOMA; Cancer, Ovarian

Evidence Section : DID06289 - MEDLINE

RScore Document Snippets
35 - [0, 0, 1, 2] Bisphenol A and polychlorinated biphenyls enhance the cancer stem cell properties of human ovarian cancer cells by activating the WNT signaling pathway.
[MEDLINE : 31918092]
(2020) Bisphenol A and polychlorinated biphenyls enhance the cancer stem cell properties of human ovarian cancer cells by activating the WNT signaling pathway. Chemosphere;Chemosphere;2020 May;246:125775

- Nonetheless, most previous studies have focused on the toxic effects of these pollutants on the proliferation, metastasis and development of ovarian cancer cells.

- Many organic pollutants increase the risk of ovarian cancer depending on their estrogenic effects.

- Bisphenol A and polychlorinated biphenyls enhance the cancer stem cell properties of human ovarian cancer cells by activating the WNT signaling pathway.


Associated Diseases - DID49494 : Generalized metabolic disorder

ZScoreRScoreEntity TypeIDNameSynonyms
3.63420113083 35 - [0, 0, 1, 2] Diseases DID49494 Generalized metabolic disorder Generalized metabolic disorder; METABOLIC DISORDERS; Diseases, Metabolic; Metabolic disease; Thesaurismosis; Metabolic disorder; Thesaurismoses; Metabolic Diseases; metabolism disorder; Disease, Metabolic; Disease of metabolism

Evidence Section : DID49494 - MEDLINE

RScore Document Snippets
25 - [0, 0, 1, 0] Bisphenol A Exposure May Induce Hepatic Lipid Accumulation via Reprogramming the DNA Methylation Patterns of Genes Involved in Lipid Metabolism.
[MEDLINE : 27502578]
(2016) Bisphenol A Exposure May Induce Hepatic Lipid Accumulation via Reprogramming the DNA Methylation Patterns of Genes Involved in Lipid Metabolism. Scientific reports;Sci Rep;2016 08;6:31331

- Accumulating evidence suggests a role of bisphenol A (BPA) in metabolic disorders.

5 - [0, 0, 0, 1] The adverse effect of 4-tert-octylphenol on fat metabolism in pregnant rats via regulation of lipogenic proteins.
[MEDLINE : 26164745]
(2015) The adverse effect of 4-tert-octylphenol on fat metabolism in pregnant rats via regulation of lipogenic proteins. Environmental toxicology and pharmacology;Environ. Toxicol. Pharmacol.;2015 Jul;40(1):284-91

- The alteration of nutritional intake and fat metabolism may affect the maintenance of pregnancy and supplementation of nutrients to the fetus, and therefore can cause severe metabolic diseases such as ketosis, marasmus and diabetes mellitus in pregnant individuals.

5 - [0, 0, 0, 1] Health risk of exposure to Bisphenol A (BPA).
[MEDLINE : 25813067]
(2015) Health risk of exposure to Bisphenol A (BPA). Roczniki Panstwowego Zakladu Higieny;Rocz Panstw Zakl Hig;2015 ;66(1):5-11

- Therefore, BPA has been shown to play a role in the pathogenesis of several endocrine disorders including female and male infertility, precocious puberty, hormone dependent tumours such as breast and prostate cancer and several metabolic disorders including polycystic ovary syndrome (PCOS).


Associated Diseases - DID44631 : infertility

ZScoreRScoreEntity TypeIDNameSynonyms
2.73067046294 30 - [0, 0, 1, 1] Diseases DID44631 infertility infertility; Infertile; Difficulty conceiving

Evidence Section : DID44631 - MEDLINE

RScore Document Snippets
25 - [0, 0, 1, 0] Estimation of plasma levels of bisphenol-A & phthalates in fertile & infertile women by gas chromatography-mass spectrometry.
[MEDLINE : 30778008]
(2018) Estimation of plasma levels of bisphenol-A & phthalates in fertile & infertile women by gas chromatography-mass spectrometry. The Indian journal of medical research;Indian J. Med. Res.;2018 Dec;148(6):734-742

- Estimation of plasma levels of bisphenol-A & amp; phthalates in fertile & amp; infertile women by gas chromatography-mass spectrometry.

5 - [0, 0, 0, 1] Chronic Exposure to Bisphenol A Affects Uterine Function During Early Pregnancy in Mice.
[MEDLINE : 27022677]
(2016) Chronic Exposure to Bisphenol A Affects Uterine Function During Early Pregnancy in Mice. Endocrinology;;2016 05;157(5):1764-74

- Although BPA has been linked to infertility and recurrent miscarriage in women, the impact of its exposure on uterine function during early pregnancy remains unclear.


Associated Diseases - DID06582 : breast neoplasm

ZScoreRScoreEntity TypeIDNameSynonyms
2.73067046294 30 - [0, 0, 1, 1] Diseases DID06582 breast neoplasm breast neoplasm; Breast tumour; Neoplasm of breast; Breast Neoplasm; Tumors, Breast; Breast Tumor; Tumor of the Breast; Tumor, Breast; mammary tumor; Breast Neoplasms; Tumor of breast; Tumour of breast; Neoplasm of the Breast; Mammary Neoplasms; Breast Tumors; NEOPLASM BREAST; Neoplasm, Breast; Breast cancer; Breast cancer; Ca breast - nos; Malignant neoplasm of breast; Malignant tumor of the breast; Mammary cancer; Primary breast cancer

Evidence Section : DID06582 - MEDLINE

RScore Document Snippets
30 - [0, 0, 1, 1] Editor's Highlight: Transcriptome Profiling Reveals Bisphenol A Alternatives Activate Estrogen Receptor Alpha in Human Breast Cancer Cells.
[MEDLINE : 28591870]
(2017) Editor's Highlight: Transcriptome Profiling Reveals Bisphenol A Alternatives Activate Estrogen Receptor Alpha in Human Breast Cancer Cells. Toxicological sciences : an official journal of the Society of Toxicology;Toxicol. Sci.;2017 08;158(2):431-443

- Editor 's Highlight: Transcriptome Profiling Reveals Bisphenol A Alternatives Activate Estrogen Receptor Alpha in Human Breast Cancer Cells.

- These findings point to the importance of better understanding the risk of adverse effects from exposure to BPA alternatives, including hormone-dependent breast cancer.


Associated Diseases - DID71361 : Obesity

ZScoreRScoreEntity TypeIDNameSynonyms
2.73067046294 30 - [0, 0, 1, 1] Diseases DID71361 Obesity Obesity

Evidence Section : DID71361 - MEDLINE

RScore Document Snippets
25 - [0, 0, 1, 0] Bisphenol A: What lies beneath its induced diabetes and the epigenetic modulation?
[MEDLINE : 30359670]
(2018) Bisphenol A: What lies beneath its induced diabetes and the epigenetic modulation?. Life sciences;Life Sci;2018 Dec;214:136-144

- Obesity, hepatic steatosis, impaired insulin signaling and pancreatic islet function could be the main results of Bisphenol A exposure.

5 - [0, 0, 0, 1] Obesogen effect of bisphenol S alters mRNA expression and DNA methylation profiling in male mouse liver.
[MEDLINE : 31683443]
(2020) Obesogen effect of bisphenol S alters mRNA expression and DNA methylation profiling in male mouse liver. Chemosphere;Chemosphere;2020 Feb;241:125092

- Environmental pollution is increasingly considered an important factor involved in the obesity incidence.


Associated Diseases - DID06945 : LIVER FATTY CHANGE

ZScoreRScoreEntity TypeIDNameSynonyms
2.73067046294 30 - [0, 0, 1, 1] Diseases DID06945 LIVER FATTY CHANGE LIVER FATTY CHANGE; Liver Steatosis; hepatic steatosis; Steatosis of liver; Hepatic lipidosis; STEATOSIS HEPATIC; LIVER FATTY; Liver, Fatty; LIVER FATTY DEGENERATION; Fatty change of liver; Fatty liver disease; Alcoholic fatty liver; Steatosis of liver (disorder)

Evidence Section : DID06945 - MEDLINE

RScore Document Snippets
25 - [0, 0, 1, 0] Bisphenol A: What lies beneath its induced diabetes and the epigenetic modulation?
[MEDLINE : 30359670]
(2018) Bisphenol A: What lies beneath its induced diabetes and the epigenetic modulation?. Life sciences;Life Sci;2018 Dec;214:136-144

- Obesity, hepatic steatosis, impaired insulin signaling and pancreatic islet function could be the main results of Bisphenol A exposure.

5 - [0, 0, 0, 1] Xenobiotic-contaminated diets affect hepatic lipid metabolism: Implications for liver steatosis in Sparus aurata juveniles.
[MEDLINE : 26382854]
(2015) Xenobiotic-contaminated diets affect hepatic lipid metabolism: Implications for liver steatosis in Sparus aurata juveniles. Aquatic toxicology (Amsterdam, Netherlands);Aquat. Toxicol.;2015 Oct;167:257-64

- Xenobiotic-contaminated diets affect hepatic lipid metabolism: Implications for liver steatosis in Sparus aurata juveniles.


Associated Diseases - DID31595 : Diabetes Mellitus, Type II

ZScoreRScoreEntity TypeIDNameSynonyms
2.73067046294 30 - [0, 0, 1, 1] Diseases DID31595 Diabetes Mellitus, Type II Diabetes Mellitus, Type II; MODY; DIABETES, MATURITY ONSET; Diabetes Mellitus, Non Insulin Dependent; NIDDM - Non-insulin dependent diabetes mellitus; Diabetes Mellitus, Type 2; AODM; Type 2 diabetes mellitus; ketosis resistant diabetes; ADULT ONSET DIABETES MELLITUS; Non-insulin dependent diabetes mellitus; DIABETES MELLITUS, NON-INSULIN DEPENDENT; type II diabetes mellitus; Non-Insulin Dependent Diabetes; Adult-Onset Diabetes Mellitus; Non-Insulin-Dependent Diabetes Mellitus; noninsulin dependent diabetes mellitus; Stable Diabetes Mellitus; Maturity onset diabetes; DIABETES MELLITUS, TYPE II; NIDDM; Diabetes Mellitus, Non-Insulin-Dependent; Ketosis-Resistant Diabetes Mellitus; Maturity-Onset Diabetes Mellitus; Type II Diabetes; Diabetes mellitus type II; Maturity Onset Diabetes Mellitus; Diabetes mellitus type 2; Vasopressin-Sensitive Diabetes Insipidus; Maturity-onset diabetes of the young; Mason-type diabetes

Evidence Section : DID31595 - MEDLINE

RScore Document Snippets
30 - [0, 0, 1, 1] Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes.
[MEDLINE : 31004310]
(2019) Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes. Molecular and cellular biochemistry;Mol. Cell. Biochem.;2019 Aug;458(1-2):171-183

- There is a striking interaction of genes and environment in the etiology of type 2 diabetes mellitus (T2DM).

- While endocrine disrupting chemicals (EDCs) like bisphenol-A (BPA) have received special attention for their mechanistic role in metabolic disruption, there is a lack of clinically relevant data on BPA levels in Asian Indians, a population which is more susceptible to type 2 diabetes mellitus (T2DM) and cardiovascular diseases.


Associated Diseases - DID40352 : tumorigenesis

ZScoreRScoreEntity TypeIDNameSynonyms
1.82713979506 25 - [0, 0, 1, 0] Diseases DID40352 tumorigenesis tumorigenesis; oncogenesis; Tumorigenesis

Evidence Section : DID40352 - MEDLINE

RScore Document Snippets
25 - [0, 0, 1, 0] Epigenome-wide DNA methylation analysis implicates neuronal and inflammatory signaling pathways in adult murine hepatic tumorigenesis following perinatal exposure to bisphenol A.
[MEDLINE : 27334623]
(2016) Epigenome-wide DNA methylation analysis implicates neuronal and inflammatory signaling pathways in adult murine hepatic tumorigenesis following perinatal exposure to bisphenol A. Environmental and molecular mutagenesis;Environ. Mol. Mutagen.;2016 07;57(6):435-46

- Epigenome-wide DNA methylation analysis implicates neuronal and inflammatory signaling pathways in adult murine hepatic tumorigenesis following perinatal exposure to bisphenol A.


Associated Diseases - DID61015 : Poor glycaemic control

ZScoreRScoreEntity TypeIDNameSynonyms
1.82713979506 25 - [0, 0, 1, 0] Diseases DID61015 Poor glycaemic control Poor glycaemic control; Poor glycemic control

Evidence Section : DID61015 - MEDLINE

RScore Document Snippets
25 - [0, 0, 1, 0] Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes.
[MEDLINE : 31004310]
(2019) Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes. Molecular and cellular biochemistry;Mol. Cell. Biochem.;2019 Aug;458(1-2):171-183

- Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes.


Associated Diseases - DID70477 : Disease

ZScoreRScoreEntity TypeIDNameSynonyms
1.82713979506 25 - [0, 0, 0, 5] Diseases DID70477 Disease Disease

Evidence Section : DID70477 - MEDLINE

RScore Document Snippets
10 - [0, 0, 0, 2] Epigenome-wide DNA methylation analysis implicates neuronal and inflammatory signaling pathways in adult murine hepatic tumorigenesis following perinatal exposure to bisphenol A.
[MEDLINE : 27334623]
(2016) Epigenome-wide DNA methylation analysis implicates neuronal and inflammatory signaling pathways in adult murine hepatic tumorigenesis following perinatal exposure to bisphenol A. Environmental and molecular mutagenesis;Environ. Mol. Mutagen.;2016 07;57(6):435-46

- This work demonstrated that epigenome-wide discovery experiments in animal models were effective tools for identification and understanding of paralagous epimutations salient to human disease.

- These tumors represent early-onset disease and lack classical sexual dimorphism in incidence.

5 - [0, 0, 0, 1] Obesogen effect of bisphenol S alters mRNA expression and DNA methylation profiling in male mouse liver.
[MEDLINE : 31683443]
(2020) Obesogen effect of bisphenol S alters mRNA expression and DNA methylation profiling in male mouse liver. Chemosphere;Chemosphere;2020 Feb;241:125092

- Endocrine disruptors (EDs) are important actors in the concept of DOHaD (Developmental Origins of Health and Disease), where epigenetic mechanisms play crucial roles.

5 - [0, 0, 0, 1] Neurodevelopmental Disorders and Environmental Toxicants: Epigenetics as an Underlying Mechanism.
[MEDLINE : 28567415]
(2017) Neurodevelopmental Disorders and Environmental Toxicants: Epigenetics as an Underlying Mechanism. International journal of genomics;Int J Genomics;2017 ;2017:7526592

- The Developmental Origin of Health and Disease (DOHaD) hypothesizes that the environment during fetal and childhood development affects the risk for many chronic diseases in later stages of life, including neurodevelopmental disorders.

5 - [0, 0, 0, 1] Long Non-Coding RNAs: A Novel Paradigm for Toxicology.
[MEDLINE : 27864543]
(2017) Long Non-Coding RNAs: A Novel Paradigm for Toxicology. Toxicological sciences : an official journal of the Society of Toxicology;Toxicol. Sci.;2017 01;155(1):3-21

- Dysregulation of lncRNAs has been implicated in various human health outcomes such as various cancers, Alzheimer 's disease, cardiovascular disease, autoimmune diseases, as well as intermediary metabolism such as glucose, lipid, and bile acid homeostasis.


Associated Diseases - DID34674 : Cardiovascular Diseases

ZScoreRScoreEntity TypeIDNameSynonyms
1.82713979506 25 - [0, 0, 1, 0] Diseases DID34674 Cardiovascular Diseases Cardiovascular Diseases; CVS disease; Cardiovascular Disorder; Disease, Cardiovascular; Diseases, Cardiovascular; Cardiovascular system disease; Cardiovascular Disorders; DISORDER CARDIOVASCULAR; Disease of cardiovascular system; Cardiovascular system diseases; Disease of subdivision of hemolymphoid system

Evidence Section : DID34674 - MEDLINE

RScore Document Snippets
25 - [0, 0, 1, 0] Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes.
[MEDLINE : 31004310]
(2019) Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes. Molecular and cellular biochemistry;Mol. Cell. Biochem.;2019 Aug;458(1-2):171-183

- While endocrine disrupting chemicals (EDCs) like bisphenol-A (BPA) have received special attention for their mechanistic role in metabolic disruption, there is a lack of clinically relevant data on BPA levels in Asian Indians, a population which is more susceptible to type 2 diabetes mellitus (T2DM) and cardiovascular diseases.


Associated Diseases - DID32555 : Atopic neurodermatitis

ZScoreRScoreEntity TypeIDNameSynonyms
1.82713979506 25 - [0, 0, 1, 0] Diseases DID32555 Atopic neurodermatitis Atopic neurodermatitis; Atopic Dermatitis; Disseminated neurodermatitis; Besnier's prurigo; ECZEMA, ATOPIC; Atopic Eczema; AD - Atopic dermatitis; DERMATITIS ALLERGIC; Allergic eczema; Allergic dermatitis; BESNIER PRURIGO; Eczema, allergic; DERMATITIS ATOPIC; Canine atopy; DERMATITIS, ATOPIC; Atopic Neurodermatitis; ECZEMA ATOPIC; Allergic (intrinsic) eczema (disorder); Atopic dermatitis (disorder); Atopic dermatitis nos (disorder); Atopic neurodermatitis (disorder); Besnier's prurigo (disorder)

Evidence Section : DID32555 - MEDLINE

RScore Document Snippets
25 - [0, 0, 1, 0] Exposure to phthalates and bisphenol A are associated with atopic dermatitis symptoms in children: a time-series analysis.
[MEDLINE : 28274229]
(2017) Exposure to phthalates and bisphenol A are associated with atopic dermatitis symptoms in children: a time-series analysis. Environmental health : a global access science source;Environ Health;2017 03;16(1):24

- Exposure to phthalates and bisphenol A are associated with atopic dermatitis symptoms in children: a time-series analysis.


Review Search Parameters

Parameter Name Values
sid

1663945102

timestamp

2022-09-21 22:43:11

query

Bisphenol A

action

association

status

Complete

query type toxin : T3D0637
target types disease : 14
found hits

14

doc count medline : 108
total hits

108

max hits

2000

synonyms bisphenol-a :


This project is supported by the Canadian Institutes of Health Research (award #111062), Alberta Innovates - Health Solutions, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Alberta, Genome British Columbia, and Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with $900 million in funding from the federal government.