Diseases : DID38503 - Diabetes mellitus

ZScoreRScoreEntity TypeIDNameSynonyms
12.6695078097 85 - [0, 0, 3, 2] Diseases DID38503 Diabetes mellitus Diabetes mellitus; DM - Diabetes mellitus; diabetes; Diabetes mellitus (disorder); Diabetes nos
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RScore Document Snippets Details
55 - [0, 0, 2, 1] Bisphenol A: What lies beneath its induced diabetes and the epigenetic modulation?
[MEDLINE : 30359670]
(2018) Bisphenol A: What lies beneath its induced diabetes and the epigenetic modulation?. Life sciences;Life Sci;2018 Dec;214:136-144

- Nowadays, endocrine disrupting chemical pollution has become one of the major concerns due to the potential role of these chemicals in provoking endocrine disorders especially type 2 diabetes.

- Bisphenol A: What lies beneath its induced diabetes and the epigenetic modulation?

- As a widespread endocrine disrupting chemical, Bisphenol A, with modest estrogenic activity can exert its detrimental effects in the different organs involved in type 2 diabetes such as pancreas, liver, adipocyte and skeletal muscles.

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25 - [0, 0, 1, 0] Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes.
[MEDLINE : 31004310]
(2019) Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes. Molecular and cellular biochemistry;Mol. Cell. Biochem.;2019 Aug;458(1-2):171-183

- Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes.

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5 - [0, 0, 0, 1] The adverse effect of 4-tert-octylphenol on fat metabolism in pregnant rats via regulation of lipogenic proteins.
[MEDLINE : 26164745]
(2015) The adverse effect of 4-tert-octylphenol on fat metabolism in pregnant rats via regulation of lipogenic proteins. Environmental toxicology and pharmacology;Environ. Toxicol. Pharmacol.;2015 Jul;40(1):284-91

- The alteration of nutritional intake and fat metabolism may affect the maintenance of pregnancy and supplementation of nutrients to the fetus, and therefore can cause severe metabolic diseases such as ketosis, marasmus and diabetes mellitus in pregnant individuals.

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This project is supported by the Canadian Institutes of Health Research (award #111062), Alberta Innovates - Health Solutions, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Alberta, Genome British Columbia, and Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with $900 million in funding from the federal government.