Diseases : DID71361 - Obesity

ZScoreRScoreEntity TypeIDNameSynonyms
11.5276430993 120 - [0, 1, 2, 4] Diseases DID71361 Obesity Obesity
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RScore Document Snippets Details
55 - [0, 1, 0, 1] Obesity aggravates toxic effect of BPA on spermatogenesis.
[MEDLINE : 28501790]
(2017) Obesity aggravates toxic effect of BPA on spermatogenesis. Environment international;Environ Int;2017 08;105:56-65

- Obesity aggravates toxic effect of BPA on spermatogenesis.

- Both bisphenol A (BPA) and obesity affect male reproductive system.

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25 - [0, 0, 1, 0] Bisphenol A: What lies beneath its induced diabetes and the epigenetic modulation?
[MEDLINE : 30359670]
(2018) Bisphenol A: What lies beneath its induced diabetes and the epigenetic modulation?. Life sciences;Life Sci;2018 Dec;214:136-144

- Obesity, hepatic steatosis, impaired insulin signaling and pancreatic islet function could be the main results of Bisphenol A exposure.

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25 - [0, 0, 1, 0] Association between prenatal bisphenol A and phthalate exposures and fetal metabolic related biomarkers: The Hokkaido study on Environment and Children's Health.
[MEDLINE : 29223775]
(2018) Association between prenatal bisphenol A and phthalate exposures and fetal metabolic related biomarkers: The Hokkaido study on Environment and Children's Health. Environmental research;Environ. Res.;2018 02;161:505-511

- Both bisphenol A and phthalates have been suggested as playing a role in obesity epidemics.

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5 - [0, 0, 0, 1] Obesogen effect of bisphenol S alters mRNA expression and DNA methylation profiling in male mouse liver.
[MEDLINE : 31683443]
(2020) Obesogen effect of bisphenol S alters mRNA expression and DNA methylation profiling in male mouse liver. Chemosphere;Chemosphere;2020 Feb;241:125092

- Environmental pollution is increasingly considered an important factor involved in the obesity incidence.

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5 - [0, 0, 0, 1] Short and long-term effects of bisphenol S (BPS) exposure during pregnancy and lactation on plasma lipids, hormones, and behavior in rats.
[MEDLINE : 31003143]
(2019) Short and long-term effects of bisphenol S (BPS) exposure during pregnancy and lactation on plasma lipids, hormones, and behavior in rats. Environmental pollution (Barking, Essex : 1987);Environ. Pollut.;2019 Jul;250:312-322

- Furthermore, the increased preference for the fat-enriched diet suggests an increased risk for obesity and its health consequences in the long term.

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5 - [0, 0, 0, 1] Exposure to bisphenol-A during pregnancy partially mimics the effects of a high-fat diet altering glucose homeostasis and gene expression in adult male mice.
[MEDLINE : 24959901]
(2014) Exposure to bisphenol-A during pregnancy partially mimics the effects of a high-fat diet altering glucose homeostasis and gene expression in adult male mice. PloS one;PLoS ONE;2014 ;9(6):e100214

- This term refers to a form of diabetes which typically develops in later life and is associated with obesity.

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This project is supported by the Canadian Institutes of Health Research (award #111062), Alberta Innovates - Health Solutions, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Alberta, Genome British Columbia, and Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with $900 million in funding from the federal government.