Diseases : DID59006 - genotoxicity

ZScoreRScoreEntity TypeIDNameSynonyms
1.31707234506 30 - [0, 0, 1, 1] Diseases DID59006 genotoxicity genotoxicity
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30 - [0, 0, 1, 1] In vitro study to evaluate the cytotoxicity of BPA analogues based on their oxidative and genotoxic potential using human peripheral blood cells.
[MEDLINE : 31173877]
(2019) In vitro study to evaluate the cytotoxicity of BPA analogues based on their oxidative and genotoxic potential using human peripheral blood cells. Toxicology in vitro : an international journal published in association with BIBRA;Toxicol In Vitro;2019 Jun;60:229-236

- Therefore, bisphenols were found capable of inducing cytotoxicity via oxidative stress and genotoxicity.

- Although Bisphenol-A (BPA) has been found to exhibit toxicological properties such as genotoxicity and oxidative stress, yet there is very little data available on its analogues.

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This project is supported by the Canadian Institutes of Health Research (award #111062), Alberta Innovates - Health Solutions, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Alberta, Genome British Columbia, and Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with $900 million in funding from the federal government.