| ZScore | RScore | Entity Type | ID | Name | Synonyms |
|---|---|---|---|---|---|
| 3.3834722195 | 60 - [0, 0, 2, 2] | Diseases | DID34674 | Cardiovascular Diseases | Cardiovascular Diseases; CVS disease; Cardiovascular Disorder; Disease, Cardiovascular; Diseases, Cardiovascular; Cardiovascular system disease; Cardiovascular Disorders; DISORDER CARDIOVASCULAR; Disease of cardiovascular system; Cardiovascular system diseases; Disease of subdivision of hemolymphoid system |
| RScore | Document | Snippets | Details |
|---|---|---|---|
| 25 - [0, 0, 1, 0] |
Cardiogenesis impairment promoted by bisphenol A exposure is successfully counteracted by epigallocatechin gallate. [MEDLINE : 31126002] |
(2019) Cardiogenesis impairment promoted by bisphenol A exposure is successfully counteracted by epigallocatechin gallate. Environmental pollution (Barking, Essex : 1987);;2019 Mar;246:1008-1019 - Exposure to the emerging contaminant bisphenol A (BPA) is ubiquitous and associated with cardiovascular disorders. |
Details |
| 25 - [0, 0, 1, 0] |
Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes. [MEDLINE : 31004310] |
(2019) Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes. Molecular and cellular biochemistry;Mol. Cell. Biochem.;2019 Aug;458(1-2):171-183 - While endocrine disrupting chemicals (EDCs) like bisphenol-A (BPA) have received special attention for their mechanistic role in metabolic disruption, there is a lack of clinically relevant data on BPA levels in Asian Indians, a population which is more susceptible to type 2 diabetes mellitus (T2DM) and cardiovascular diseases. |
Details |
| 5 - [0, 0, 0, 1] |
Genome-wide alteration in DNA hydroxymethylation in the sperm from bisphenol A-exposed men. [MEDLINE : 28582417] |
(2017) Genome-wide alteration in DNA hydroxymethylation in the sperm from bisphenol A-exposed men. PloS one;PLoS ONE;2017 ;12(6):e0178535 - The hyper-hMRs affected genes were enriched in pathways associated with nervous system, development, cardiovascular diseases and signal transduction. |
Details |
| 5 - [0, 0, 0, 1] |
Maternal bisphenol a exposure impacts the fetal heart transcriptome. [MEDLINE : 24586524] |
(2014) Maternal bisphenol a exposure impacts the fetal heart transcriptome. PloS one;PLoS ONE;2014 ;9(2):e89096 - Our results intensify concerns about the role of BPA in the genesis of human metabolic and cardiovascular diseases. |
Details |
Liu Y., Liang Y., Wishart D.S. (2015) PolySearch 2.0: A significantly improved text-mining system for discovering associations between human diseases, genes, drugs, metabolites, toxins, and more. Nucleic Acids Res. 2015 Jul 1;43(Web Server Issue):W535-42.
Cheng D., Knox C., Young N., Stothard P., Damaraju S., Wishart D.S. (2008) PolySearch: a web-based text mining system for extracting relationships between human diseases, genes, mutations, drugs and metabolites. Nucleic Acids Res. 2008 Jul 1;36(Web Server Issue):W399-405.
This project is supported by the Canadian Institutes of Health Research (award #111062), Alberta Innovates - Health Solutions, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Alberta, Genome British Columbia, and Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with $900 million in funding from the federal government.