| ZScore | RScore | Entity Type | ID | Name | Synonyms |
|---|---|---|---|---|---|
| 5.86346577967 | 90 - [0, 0, 3, 3] | Diseases | DID06945 | LIVER FATTY CHANGE | LIVER FATTY CHANGE; Liver Steatosis; hepatic steatosis; Steatosis of liver; Hepatic lipidosis; STEATOSIS HEPATIC; LIVER FATTY; Liver, Fatty; LIVER FATTY DEGENERATION; Fatty change of liver; Fatty liver disease; Alcoholic fatty liver; Steatosis of liver (disorder) |
| RScore | Document | Snippets | Details |
|---|---|---|---|
| 50 - [0, 0, 2, 0] |
Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet-induced hepatic steatosis. [MEDLINE : 25748669] |
(2015) Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet-induced hepatic steatosis. Toxicology and applied pharmacology;Toxicol. Appl. Pharmacol.;2015 Apr;284(2):101-12 - Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet-induced hepatic steatosis. - Developmental bisphenol A (BPA) exposure increases adulthood hepatic steatosis with reduced mitochondrial function. |
Details |
| 25 - [0, 0, 1, 0] |
Bisphenol A: What lies beneath its induced diabetes and the epigenetic modulation? [MEDLINE : 30359670] |
(2018) Bisphenol A: What lies beneath its induced diabetes and the epigenetic modulation?. Life sciences;Life Sci;2018 Dec;214:136-144 - Obesity, hepatic steatosis, impaired insulin signaling and pancreatic islet function could be the main results of Bisphenol A exposure. |
Details |
| 10 - [0, 0, 0, 2] |
Downregulation of miR-192 causes hepatic steatosis and lipid accumulation by inducing SREBF1: Novel mechanism for bisphenol A-triggered non-alcoholic fatty liver disease. [MEDLINE : 28483554] |
(2017) Downregulation of miR-192 causes hepatic steatosis and lipid accumulation by inducing SREBF1: Novel mechanism for bisphenol A-triggered non-alcoholic fatty liver disease. Biochimica et biophysica acta. Molecular and cell biology of lipids;Biochim Biophys Acta Mol Cell Biol Lipids;2017 Sep;1862(9):869-882 - MiR-192 mimic and lentivirus-mediated overexpression of miR-192 improved BPA-induced hepatic steatosis by suppressing SREBF1. - Downregulation of miR-192 causes hepatic steatosis and lipid accumulation by inducing SREBF1: Novel mechanism for bisphenol A-triggered non-alcoholic fatty liver disease. |
Details |
| 5 - [0, 0, 0, 1] |
Xenobiotic-contaminated diets affect hepatic lipid metabolism: Implications for liver steatosis in Sparus aurata juveniles. [MEDLINE : 26382854] |
(2015) Xenobiotic-contaminated diets affect hepatic lipid metabolism: Implications for liver steatosis in Sparus aurata juveniles. Aquatic toxicology (Amsterdam, Netherlands);Aquat. Toxicol.;2015 Oct;167:257-64 - Xenobiotic-contaminated diets affect hepatic lipid metabolism: Implications for liver steatosis in Sparus aurata juveniles. |
Details |
Liu Y., Liang Y., Wishart D.S. (2015) PolySearch 2.0: A significantly improved text-mining system for discovering associations between human diseases, genes, drugs, metabolites, toxins, and more. Nucleic Acids Res. 2015 Jul 1;43(Web Server Issue):W535-42.
Cheng D., Knox C., Young N., Stothard P., Damaraju S., Wishart D.S. (2008) PolySearch: a web-based text mining system for extracting relationships between human diseases, genes, mutations, drugs and metabolites. Nucleic Acids Res. 2008 Jul 1;36(Web Server Issue):W399-405.
This project is supported by the Canadian Institutes of Health Research (award #111062), Alberta Innovates - Health Solutions, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Alberta, Genome British Columbia, and Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with $900 million in funding from the federal government.