Diseases : DID23789 - Stein-Leventhal Syndrome

ZScoreRScoreEntity TypeIDNameSynonyms
2.86482405307 55 - [0, 0, 1, 6] Diseases DID23789 Stein-Leventhal Syndrome Stein-Leventhal Syndrome; POLYCYSTIC OVARIAN SYNDROME; Stein Leventhal Syndrome; Sclerocystic ovary syndrome; STEIN-LEVENTHAL SYNDROME; Polycystic ovarian disease; PCOD - Polycystic ovarian disease; Polycystic Ovary Syndrome; Polycystic ovaries; polycystic ovary disease; PCOS; polycystic ovary disorder; Stein - Leventhal syndrome; polycystic ovary; Sclerocystic Ovarian Degeneration; Multicystic ovaries; Polycystic ovaries (disorder); Stein-leventhal synd.; Stein-leventhal synd.
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RScore Document Snippets Details
50 - [0, 0, 1, 5] Urinary concentration of personal care products and polycystic ovary syndrome: A case-control study.
[MEDLINE : 30265948]
(2019) Urinary concentration of personal care products and polycystic ovary syndrome: A case-control study. Environmental research;Environ. Res.;2019 01;168:48-53

- We performed a case-control study to explore the association between the concentrations of certain emerging contaminants (organic UV filters, bisphenol A, and triclosan) and the risk of PCOS.

- Urinary concentration of personal care products and polycystic ovary syndrome: A case-control study.

- Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorder among females of reproductive age.

- Urine samples were collected from 40 women with PCOS (case group) and 83 healthy women (control group).

- However, with stratification according to body mass index, one organic UV filter - octocrylene (OC) was significantly associated with PCOS in women with BMI ≥ 24 (adjusted OR = 1.512, 95 % CI: 1.043, 2.191).

- We conclude that there is positive association between OC and PCOS risk in obese and overweight women.

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5 - [0, 0, 0, 1] Health risk of exposure to Bisphenol A (BPA).
[MEDLINE : 25813067]
(2015) Health risk of exposure to Bisphenol A (BPA). Roczniki Panstwowego Zakladu Higieny;Rocz Panstw Zakl Hig;2015 ;66(1):5-11

- Therefore, BPA has been shown to play a role in the pathogenesis of several endocrine disorders including female and male infertility, precocious puberty, hormone dependent tumours such as breast and prostate cancer and several metabolic disorders including polycystic ovary syndrome (PCOS).

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This project is supported by the Canadian Institutes of Health Research (award #111062), Alberta Innovates - Health Solutions, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Alberta, Genome British Columbia, and Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with $900 million in funding from the federal government.