Diseases : DID31595 - Diabetes Mellitus, Type II

ZScoreRScoreEntity TypeIDNameSynonyms
3.35773744854 60 - [0, 0, 2, 2] Diseases DID31595 Diabetes Mellitus, Type II Diabetes Mellitus, Type II; MODY; DIABETES, MATURITY ONSET; Diabetes Mellitus, Non Insulin Dependent; NIDDM - Non-insulin dependent diabetes mellitus; Diabetes Mellitus, Type 2; AODM; Type 2 diabetes mellitus; ketosis resistant diabetes; ADULT ONSET DIABETES MELLITUS; Non-insulin dependent diabetes mellitus; DIABETES MELLITUS, NON-INSULIN DEPENDENT; type II diabetes mellitus; Non-Insulin Dependent Diabetes; Adult-Onset Diabetes Mellitus; Non-Insulin-Dependent Diabetes Mellitus; noninsulin dependent diabetes mellitus; Stable Diabetes Mellitus; Maturity onset diabetes; DIABETES MELLITUS, TYPE II; NIDDM; Diabetes Mellitus, Non-Insulin-Dependent; Ketosis-Resistant Diabetes Mellitus; Maturity-Onset Diabetes Mellitus; Type II Diabetes; Diabetes mellitus type II; Maturity Onset Diabetes Mellitus; Diabetes mellitus type 2; Vasopressin-Sensitive Diabetes Insipidus; Maturity-onset diabetes of the young; Mason-type diabetes
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30 - [0, 0, 1, 1] Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes.
[MEDLINE : 31004310]
(2019) Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes. Molecular and cellular biochemistry;Mol. Cell. Biochem.;2019 Aug;458(1-2):171-183

- There is a striking interaction of genes and environment in the etiology of type 2 diabetes mellitus (T2DM).

- While endocrine disrupting chemicals (EDCs) like bisphenol-A (BPA) have received special attention for their mechanistic role in metabolic disruption, there is a lack of clinically relevant data on BPA levels in Asian Indians, a population which is more susceptible to type 2 diabetes mellitus (T2DM) and cardiovascular diseases.

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25 - [0, 0, 1, 0] Urinary concentrations of environmental phenols and their association with type 2 diabetes in a population in Jeddah, Saudi Arabia.
[MEDLINE : 29960220]
(2018) Urinary concentrations of environmental phenols and their association with type 2 diabetes in a population in Jeddah, Saudi Arabia. Environmental research;Environ. Res.;2018 10;166:544-552

- A few epidemiologic studies suggest that exposure to bisphenol A (BPA) is associated with type 2 diabetes mellitus (T2DM).

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5 - [0, 0, 0, 1] Biomonitoring of human exposures to chlorinated derivatives and structural analogs of bisphenol A.
[MEDLINE : 26521216]
(2015) Biomonitoring of human exposures to chlorinated derivatives and structural analogs of bisphenol A. Environment international;Environ Int;2015 Dec;85:352-79

- Up to date findings indicated the association of ClxBPA with metabolic conditions, such as obesity, lipid accumulation, and type 2 diabetes mellitus, particularly in in-vitro and in-vivo studies.

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This project is supported by the Canadian Institutes of Health Research (award #111062), Alberta Innovates - Health Solutions, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Alberta, Genome British Columbia, and Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with $900 million in funding from the federal government.